5-Lipoxygenase contributes to the progression of hepatocellular carcinoma

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5-Lipoxygenase contributes to the progression of hepatocellular carcinoma.

5-Lipoxygenase (5-LOX) has been implicated in the development and progression of lung, pancreatic and esophageal cancers. However, its role in hepatocellular carcinoma (HCC) remains unclear. This study aimed to explore the role of 5-LOX in the pathogenesis of HCC. The expression of 5-LOX was detected in human HCC, HepG2 cells and diethylnitrosamine (DEN)-induced rat HCC using immunohistochemist...

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ژورنال

عنوان ژورنال: Molecular Medicine Reports

سال: 2011

ISSN: 1791-2997,1791-3004

DOI: 10.3892/mmr.2011.547